Sentence examples for background mutation frequency in from inspiring English sources

The background mutation frequency in the lacI transgene of BigBlue™ rat was found to be approximately an order of magnitude higher than that of hprt [Skopek et al., 1996].

(Longer [TC/AG] alleles could not be analyzed using the in vitro assay due to the high background mutation frequency of the single-stranded DNA preparations).

μ A variable representing the background mutation frequency of the tissue.

(We are unable to analyze mutagenesis at [AT/TA]n motifs of mature length using our experimental system due to high background mutation frequencies, so this motif was not analyzed in this assay).

For each template strand, the polymerase error frequency was calculated by subtracting the ssDNA background mutation frequencies from the observed pol β HSV- tk mutation frequencies.

For each template, the polymerase error frequency was calculated by subtracting the ssDNA background mutation frequencies from the observed pol β HSV-tk mutation frequencies.

We found that expression of MBD4tru roughly doubles mutation frequency in cells even on the background of MMR defect, on agreement with the dominant negative hypothesis.

(a) γ-irradiation induced mutation frequency in BaF3 cells treated with or without 1 μM imatinib.

Therefore, we analyzed mutation frequency in cells transfected with an imatinib-resistant bcr-abl mutant (Bcr-AblT315I).

Influence of imatinib on mutation frequencies in Bcr-Abl-positive and Bcr-Abl-negative cells.

Furthermore, we wanted to investigate the LKB1 mutational frequency in different histologies and ethnic backgrounds, and assess their correlation to smoking history, gender, stage, survival, and other oncogenic mutations in NSCLC.