Sentence examples for background level of phosphorylation from inspiring English sources
We deduced that the persistent phosphorylation of Rfa2-NΔ40 in pph3Δ cells before and after HU treatment might reflect the background level of phosphorylation as seen in normal cells.
Even in the U87-C cells, which produce high levels of PDGF-C, there was only a background level of PDGFRβ phosphorylation, indicating a lack of autocrine signaling (Figure 1C).
There is no effect of gefitinib on the very low background level of STAT3 phosphorylation in the EGFRvIII-expressing cell line.
We have recently reported that untreated normal or tumor cells in culture exhibit a "background" level of DNA damage signaling (DDS) revealed as histone H2AX phosphorylation on Ser139 and activation of Ataxia Telangiectasia mutated protein kinase (ATM) through phosphorylation on Ser1981 [ 32- 34].
Cells apparently contain significant background levels of phospho-S320-HSF1 phospho-S320-HSF1 phospho-S320-HSF1iandly after heat shock, before decaying back to basal levels by 2 hr recovery at 37°C, correlating well with the phosphorylationased trans-actincreasedy heat shock (Fimmediately
For cyclin concentrations less than the threshold, he observed only background levels of histone H1 phosphorylation, but as soon as the cyclin level was greater than the threshold, the extract abruptly exhibited a high rate of histone phosphorylation, which increased further with increasing cyclin concentration.
Background levels of genetic alterations.
Because the byproducts of oxidative phosphorylation reactions can diffuse from mitochondria, reach the nuclear DNA and induce damage [ 3], this cellular process accounts for the background levels of oxidative damage to DNA detected in normal tissue [ 4, 5].
