Sentence examples for background level of expression from inspiring English sources

Natural heat shock promoters constitute a simple inducible misexpression system, the main disadvantage is a high background level of expression.

In order to determine the background level of expression, we investigated the number of mRNAseq reads mapping to intergenic regions.

The misassigned reads were spread over approximately 2500 genes on average; i.e., they contribute to a low background level of expression, although genes for nuclear proteins tended to have more such reads than other genes (Additional file 7: Table S6A).

Likewise, in the endometrium tamoxifen, but not raloxifene, may have oestogenic-like effects due to recruitment or coactivators to a subset of genes, and this aspect may vary in different tissues depending on the background level of expression of coactivators such as SRC-1 [ 21].

Background levels of expression and variability for mRNA transcripts, proteins, and metabolites in human tissues are currently not known but must be defined if toxicogenomics methods are to be used to assess personal exposures in epidemiologic studies.

Second, the effect of HDAC inhibitors on CD69 expression appeared to be dependent on the background level of CD69 expression, i.e., in donors with low proportions of CD69+ T-cells HDAC inhibitors induced only minimal increases, whereas CD69 expression was more inducible in donor cells with higher background proportions of CD69+ T-cells.

In mice, the background level of SCD1 expression correlates with predisposition to liver carcinogenesis; rodents with higher levels of SCD1 are more susceptible to induction of cancer [10].

The parameter k determines the background level of constitutive expression across both loci.

pxc1-3 displayed only background level of PXC1 expression, suggesting that this allele might represent a null mutant.

As these clones showed a somewhat higher background level of RFP expression (especially clone CL [pTcrRNA-T7Tet]:RFP C6), we tested the luciferase construct in this background.

The instrument settings were calibrated for each run so as to obtain a background level of EGFP expression of ~1% for control cells.