Exact(3)
The participants in that workshop strongly recommended that the NTP discontinues use of the F344/N because of its high background incidences of certain types of tumors (i.e., Leydig cell tumors and mononuclear cell leukemia), unresolved issues regarding its declining fertility, occurrence of sporadic seizures, and chylothorax.
For example, the F344/N rat typically used by the NTP has high background incidences of testicular Leydig cell tumors and mononuclear cell leukemia, along with unresolved issues about declining fertility, sporadic seizures, and chylothorax (accumulation of lymphatic fluid in the pleural cavity, which can result from lymphoma).
Results of estimating the distribution of background rates of NGI and historical HCGI among beaches confirm this and allow an evaluation of their relative precisions as well as precision of the ratio between the background incidences of contemporary NGI and pre-1986 HCGI.
Similar(57)
16 17 Yet an increase in the incidence rate of breast cancer could reflect overdiagnosis as well as a change in the background incidence trend or lead time from early detection of both prevalent and incident cancers.
If these subjects had a high rate of positive discography, the high background incidence of common backache would allow many positive tests in patients in whom discogenic processes were unrelated to their severe CLBP illness.
MMR vaccination did not cause any increase over the background incidence of GBS, and no clustering of cases of GBS occurred at any time point after administration of MMR vaccine.
We speculate that background incidence of malaria was higher in the rural villages of the community based arm than the villages with a static health facility.
Over these 7.5 years, in the absence of any culling, an idealised circular area of 150 km2, with a herd density of 1.25/km2 and a background incidence of 0.08 breakdowns/herd/year, would be expected to experience 112.5 herd breakdowns.
Both rates will increase with increasing background incidence.
The background incidence of malignancy was low and stable.
With the breast cancer incidence increasing over time [ 2], this estimated background incidence will consequently increasingly underestimate the true background incidence.
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