Interestingly, recent studies on heart phenotypes in a trisomic background implicate a significant role for ciliome genes in the etiology of DS-associated AVSD (Ripoll et al. 2012; Ramachandran et al. 2014; Li et al. 2015).
Whether they liked it or not, Londoners of all backgrounds were implicated in the carnage of the trenches.
Background: Involved or implicated in a wide spectrum of diseases, trypsin-like serine proteases comprise well studied drug targets and anti-targets that can be subdivided into two major classes.
The causative allele(s) remains to be identified and probably occurs on the background of the implicated PRNP haplotype.
However, in both cases simulations were used to implicate background selection as the model that best fits the observed diversity data.
We aimed to characterize in thyroid cancer cell lines with different genetic background those molecules implicated in proliferation/survival using RNAi targeting BRAF and the kinase inhibitor sorafenib.
In many respects, the ADHD/SUD group and the general SUD group, showed similar clinical impairments and did not differ in socio-demographic background which could implicate need of intensive clinical intervention in both groups to reduce their burden of harm.
The higher-resolution SNP array also allowed Leary and colleagues [ 3] to estimate an average number of 18 copy-number aberrations (7 HDs and 11 high-level amplifications) that were altered significantly above the background mutation rate, implicating about 24 genes that are driving tumour progression.
The exclusive detection of m.14484T→C on haplogroup J implicates the background mtDNA haplotype in mutagenesis.
Background: Enjoyment has been implicated as a determinant of physical activity among youth, but advances in understanding its importance have been limited by the use of measures that were not adequately validated.
