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The background frequency was determined on 100,000 pseudo-SBE sequences.
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The background frequency is determined by shuffling each sequence from the promoter database which results in a randomized DNA sequence with the same nucleotide content.
The mitotic recombination frequency was determined by FACS analysis.
The crossing frequency was determined by counting the number of animals' crossing to the neighboring zone.
Exacerbation frequency was determined from diary cards.
Allele frequency was determined by gene counting.
Mutation frequency is determined by fluctuation assays.
For each genome, whole-genome and per-chromosome tri-nucleotide frequencies were determined using a custom script to obtain an order-two Markov background from the whole-genome and chromosome sequences respectively.
Allele and genotype frequencies were determined for 24,066 participants.
Allele and genotype frequencies were determined.
Allele frequencies were determined by direct counting.
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