Exact(4)
One strategy may be to use error propagation to evaluate background correction, and only background correct the spots where the bias is large, thus not increasing the variance of all spots, but still removing the bias for some of the worst affected spots.
In the VSN algorithm [ 8] a generalized log transform is used to background correct the data.
These composite samples were analyzed by ICP-MS and used to background correct the results of spiked water experiments.
It is common practice to transform, normalize and background correct the intensities from DNA arrays although there is no widespread agreement on the best procedures (Allison et al. 2006).
Similar(4)
All arrays were background corrected using local background correction and normalized using Lowess normalization [ 87].
Raw feature intensities were background corrected using the RMA background correction algorithm [ 21, 22].
Expression values were background corrected using the GCRMA algorithm (Robust Multi-array analysis with correction for GC content) [19], [20].
Intensities are background corrected and normalized to incident laser power.
Related(1)
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