Sentence examples for background alignment from inspiring English sources
This is indicated by the shared hydrophobic residues (L/I 707, L712) between ErbB kinases (Foreground alignment in Figure 1) and RTKs (Background alignment in Figure 1).
The algorithm uses a sliding window method to determine if a query sequence from an individual matches sequences in a background alignment of viral sequences derived from that individual and his partner.
Notably, the residues identified by the BPPS procedure are highly conserved in the ErbB family (foreground alignment) and strikingly different in receptor tyrosine kinases outside of the ErbB family (background alignment) (Figure 1).
Among these residues, Q791 in the inter-lobe linker contributes the most (indicated by the height of the histogram in Figure 1) to ErbB functional divergence, since none of the RTKs outside of the ErbB family conserve a glutamine at the 791 position (Background alignment in Figure 1).
For these lines, both the best overall match and the best secondary match were to one or both of the reported intercross background with alignment scores of 0.7 or greater (OB1xB3 had a slightly lower alignment score due to known contamination by Chinese Hamster Ovary feeder cells, personal communication from Rosann Farber, Additional file 1).
There are many potential specificity determining residues, i.e. capable of separating the subfamilies, that can be seen highlighted in black background at alignment positions 23, 32, 38, 39, 40, 41 and 49.
Preliminary background normalization, image alignment, and reconstruction were performed using the XMreconstructor software package from Xradia.
Furthermore, mass data were exported to ProfileAnalysis 1.1 software (Bruker), which allowed for peak alignment, background noise subtraction and data reduction.
Advanced approaches, which are being continuously developed, offer improved homology detection and a reduced background noise in alignment results [12] [15].
On the basis of single-fluorophore control experiments, green-to-red bleed-through corrections of 10% for were employed; following background subtraction and alignment, 10% of the EGFP signal was subtracted from dsRed images.
Therefore, the rareness of invariant sequences differs depending on the conservation background in each alignment.
