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For this, frames from a 4 s time window, starting 5 s after stimulus delivery (assumed to be background activity) was used.
Any focal FDG uptake in a pulmonary lesion or in a mediastinal node higher than the surrounding background activity was used as a PET criterion for malignancy.
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Background activity was measured using a spherical VOI with a diameter of 60 mm, placed in the center of the phantom.
Background activity was measured using extracts from vector only transfected control cells.
Since the background activity was defined experimentally, the algorithm used to fit this curve (Grafit 5; Erithacus Software) estimated (i) the concentration of dexamethasone needed for half-maximal activation (EC50); (ii) the maximal response (Rmax), and (iii) the Hill Coefficient.
For quantification of standard PET-derived parameters such as the tumor-to-background ratio, the background activity is assessed using a region of interest (ROI) or volume of interest (VOI) in unaffected brain tissue.
This background activity was then accounted for by including a constant term in the model used for curve fitting.
2 The aEEG background activity was classified according to published voltage criteria and by background pattern.
Similarly, reactive cEEG background activity was associated with recovery, whereas nonreactive cEEG background activity during TH predicted death [ 8].
Any signal in the control strain is due to background activity and is used to correct the measuring strain signal.
No activity in the background was used.
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