Sentence examples for backbones Morpholinos from inspiring English sources
Because of their completely unnatural backbones, Morpholinos are not recognized by cellular proteins.
The unnatural backbones of morpholinos preclude their degradation by the cellular machinery.
The nonribose-based backbone renders morpholinos insensitive to enzymatic degradation.
The entire backbone of a Morpholino is made from these modified subunits.
Antisense molecules with significantly modified backbones such as peptide nucleic acids (PNA), methoxyethoxy (MOE) and locked nucleic acids (LNA), or morpholino oligos, rendering them RNase H inactive, are able to modulate mRNA splicing when targeting intron-exon junctions in pre-mRNA [ 1- 7].
All experiments were conducted using co-injection of both morpholinos.
Sea plants, animals without backbones.
Application of morpholinos was performed as previously described in ref.13.
Animals Without Backbones.
Unlike worms, they also have strong backbones.
