Aided by its cofactor, pyridoxal phosphate, NFS1 supplies sulfur by removing it from cysteine residues, and ISCU provides the backbone structure and the cysteine ligands upon which a new cluster consisting of covalently bound iron and inorganic sulfur is synthesized (Raulfs et al., 2008; Py and Barras, 2010; Bandyopadhyay et al., 2008; Lill, 2009).
It therefore serves as a backbone upon which data and its associated metadata can be 'attached'attached
On the other hand, overexpression or uncontrolled expression of PH-20 can cause great havoc in the extracellular matrix of connective tissues, since the filamentous molecule of HA serves as a backbone upon which other macromolecules associate.
A MAP is made up of a hepta lysine backbone upon which are built eight copies of the same peptide sequence (in this case 8 copies of Ro273 289).
And, finally, it can act as a syntactic backbone upon which decorations from other domains (say feature structures) can be grafted.
Importantly, endocrine therapy is an important backbone upon which targeted therapy combinations will be built.
For years the Enterprise Service Bus ESBB) has been seen as a corporate integration and messaging backbone upon which application architectures are built.
Within the abundant extracellular matrix of articular cartilage, the long, filamentous HA molecules form the backbone upon which the viscoelastic aggrecan molecules align to form aggregates, a supramolecular organization that immobilizes aggrecans at very high concentrations within the collagen network, thereby providing remarkable biomechanical properties to the articular tissue [ 5].
The first, a pre-produced track, forms MOMENTUM's musical backbone upon which the other layers are generated in real time.
And General Sisi insisted Tuesday that it would remain "the solid mass and the backbone upon which rest the Egyptian state's pillars".
