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Other methods, such as using BimS as a common backbone to study the BH3 helices by replacing the Bim BH3 sequence with that of the BH3-only protein to be studied have been used successfully in the past.
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In order to apply PCA/nMDS, we chose to work with backbone dihedral angles (to study local structure formation) and <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0009890.e039.PNG" class= inline-graphic"/> coordinates (to study tertiary structure formation).
"We take backbone samples to the lab to study how sharks age," Dr. Natanson said.
We previously developed and characterized a panel of small molecule affinity probes based on the L458 backbone which can be used to study the composition of active γ-secretase complexes [25].
Long has used Tadros to study the evolution of backbones, testing the idea that by making ancient fish stiffer, backbones made them faster and hence better at collecting food or evading predators.
At domain insertion sites, geometry of the polypeptide backbone was studied to assign spatially proximal residues to the ancestral domain.
By excitation of the PF side-chains energy transfer to the P3HT backbone is studied.
The effect of every parameter that describes the backbone is studied separately in order to identify the sensitivity of the demand when the system is subjected to pulse-like ground motions.
A side-chain liquid crystalline polymer (LCP) based on the 4-hydroxy-4′-methoxy-α-methylstilbene mesogen attached through a flexible spacer of eight methylenic units to a poly methyl acrylate) backbone is studied via solid-state 13C nuclear magnetic resonance (n.m.r).
Mobility of the main-chain backbone is studied in the isotactic PVA model.
This result indicates a surface-induced stiffening of the comb backbone, further studied through the persistence length lpers.
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