Sentence examples for backbone to prevent from inspiring English sources

Taken together, these findings suggest that a state of the art plasmid vector for gene delivery into mammalian cells should be composed of a promoter element that is depleted of CpG islands in order to minimize silencing phenomena, and a CpG depleted vector backbone to prevent undesired stimulatory effects on the innate immune system [ 16, 22].

The incredible leap we have faced in the understanding of the basic mechanisms of RNAi has brought a solution for most of the harmful effects identified previously, e.g., a 2′-OMe backbone modifications to prevent off-target effects.

The ionophore is therefore covalently bound to the polystyrene backbone so as to prevent gradual loss to the analyte solution.

This conformation is supposed to limit the access of PGs to the pectin backbone and therefore to prevent pectin degradation [ 31].

This copolymer, designed to preserve the backbone planarity of polythiophenes and to prevent a close packing arrangement through the non-regioregular insertion of the bulky substituted monomer, shows high PL quantum yield in the solid state and in solution aggregates.

Further, to prevent the backbone of the active site from moving considerably during the gradient-based minimization, the Cα atoms are restrained to within 0.5 Å of their original positions.

One of the purposes of backbone modifications of the SSO is to prevent mRNA degradation by RNA interference.

WAX, on the other hand, has a high degree of arabinosyl substituents present on the β-(1 → 4 -linked xylan backbone [ 39], which has been shown to prevent association with cellulose chains [ 4 -linked

According to some experts, the electoral system has developed a number of safeguards over the past few decades to prevent someone with independence and backbone from occupying the Presidency.

Providers have to lease connectivity from the backbone and, as such, they're forced to add caps to prevent us users from sucking down too much data and bankrupting them.

Zhang et al. created a polyvalent scaffold using polyadenine sequences to prevent nonspecific and undesired base pairing within the backbone.