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She suggested a "backbone" strategy of bringing people already advanced in certain policies and strategies into alignment with the commissioners who created the plan.
In the current study, it has been demonstrated that an engineered peptide backbone strategy could be utilized to obtain potent, selective, and stable melanocortin receptor ligands.
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OS differences between complex and point NOTCH1 mutations were more marked in the patients treated with the BFM protocols backbone strategies (27.3% vs. 62.5%; p = 0.041).
One-hundred and one patients were treated according to Brazilian Group for Treatment of Childhood Leukaemia (GBTLI-99), while 37 were treated according to the ALL-Berlin-Frankfurt-Munster (BFM) protocols backbone strategies, as described elsewhere [ 16, 17].
This allowed a backbone assignment strategy in which the identification of individual amino acid resonances was confirmed by a combination of CBCA CO NH and HNCO triple-resonance experiments.
Susan has written three books: "How to Grow a Backbone: 10 Strategies for Gaining Power and Influence at Work", "Life.
Many novel backbone protection strategies have been developed but the increased steric hindrance that accompanies the introduction of a secondary amine into a sequence prohibits quantitative coupling using standard conditions (except with glycine) and has limited the wider adoption of these new backbone protection strategies.
Herein, we employed two backbone-based strategies to modify the N-terminus of tGLP-1.
Structural modification through incorporation of thermally stable, addition curable groups on the novolac backbone is one strategy.
Broadcasting out of two studios built within the Kensington offices of the Independent and Evening Standard, the channel's five-and-a-half hours of local news and current affairs forms the backbone of its strategy.
"We are investing in our rapidly progressing pipeline and the key platforms that are the backbone of our strategy to return to growth," said chief executive Pascal Soriot.
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