Sentence examples for backbone pattern from inspiring English sources
One of the ligands, the synthetic peptide FAPGVFPYM (1BZ9), highly deviates from the backbone pattern, especially at p5, rising up out of the cleft (Figure S4).
Comprehensive evaluation of all possible analogues based on the ααβ, αααβ, or ααβαααβ backbone pattern (14 α/β-peptides in total) revealed two that retained affinity for both partner proteins.
α/β-Peptides 5 and 6a– d contain ααβαααβ (5) or αααβ (6a– d) backbone patterns, which are analogous to the patterns used in Bim BH3-derived peptides 2 and 3a– d, respectively.
Five years ago, the backbone branching pattern of the evolutionary tree for one of the largest groups of insects, moths and butterflies (Lepidoptera), was still for the most part unresolved.
Hydrogen bonding restraints were added for residues in secondary structural elements that were unambiguously predicted by Talos+, and that showed the characteristic backbone NOE pattern for these secondary structural elements.
The conformational search provides a wide variety of folding patterns which makes the class of ε-peptides interesting for a rational peptide design by selection of suited backbone substituent patterns.
The backbone entropy patterns of amino acids within helix, sheet or coil form clusters that recapitulate the branching and hydrogen bonding properties of the side chains in the secondary structure type.
However, a small subset of subjects with extensive N t RTI backbone TDR patterns were likely to experience virologic failure.
Overall, TDRs did not affect virologic response for subjects on a boosted PI by week 48; however, a small subset of subjects with extensive NRTI backbone TDR patterns experienced virologic failure.
Overall, there is a remarkable agreement between the backbone protection patterns derived from the high-resolution NMR and top down HDX MS measurements.
We have conducted α-peptide vs α/β-peptide comparisons involving higher β residue content, focusing on molecules with αααβ and ααβαααβ backbone repeat patterns.
