This relatively broad band contains contributions from the entire polypeptide backbone, which in the case of the WW domain includes β-sheet, β-turn, and random coil structure.
However, if the degree of v i is 2 in T, (v i,v i−1) is not an edge in the backbone, the case in which we say that the first edge is null.
After crosslinking and degradation, the hydrogel network is degraded into the components that comprise the polymer network backbone; for example, in the case of PEG-PLA diacrylate hydrogels, the degradation products are PEG, polyacrylate, and lactic acid.
The trends in rate constants detected for catalysis and HDX are believed to depend on very similar phenomena, that is, the probability of achieving a subset of protein conformers among a very large number of rapidly interconverting conformers that are suited to the measured parameter (H-transfer for catalysis vs exposure of an amide backbone to solvent in the case of HDX).
This could be either due to the fact that no trajectory smoothing was used on the number of backbone hydrogen bonds (which in the case of a discrete variable like Q eventually may lead to an artificial lumping of states with overlapping boundaries, as shown in Fig. S16 in Data S1), or to differences in the force fields.
They formed the backbone of the case against Habré.
And like the list of songs on the back of a record, the table of contents provided the book with its backbone: in Paley's case, the first three titles -- "Wants," "Debts," "Distance" -- sounded like a poem.
This was followed by digestion to prevent amplification of internal viral fragments (from the 5' LTR) and plasmid backbone with SacI and DpnI in the case on HIV, and XmaI and DpnI in the case of EIAV.
Today, the backbone in all cases of suspicious or proven CMPD should be screening for the JAK2V617F mutation status by PCR, e.g., by a melting curve light cycler assay [ 66].
A number of alternatives for service differentiation and QoS provisioning have been proposed and standardized, but in the case of backbone, transport networks the DiffServ architecture has prevailed, due to its scalability and deployment feasibility.
