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Finally, nicks in the associated DNA fragment can influence protein binding because proteins interact with the phosphate backbone, in addition to the bases.
On the other hand, secondary structure can be defined using geometric features such as distances and dihedral angles of Cα atoms along the backbone in addition to other local structural features.
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In contrast to the seed layer deposited by MS, the more uniform seed layer deposited by ALD resulted in ZnO branches with better crystallinity grown on the whole sidewall of the Si backbones, in addition to the stronger light absorption and higher photodegradation efficiency of MB for its larger surface area and higher surface curvature effect.
These compounds contain atoms such as oxygen, nitrogen, or sulfur in their backbone chains, in addition to carbon.
Instead, pinning is found to be a consequence of SAM backbone polarization in addition to local charge transfer at the organic−organic interface.
Syntheses of the octadentate ligands 3,4,3-LI-IAM-1,2-HOPO and 3,4,3-LI-1,2-HOPO-IAM, where the chromophores are attached to different positions in the (LI = linear) spermine backbone, are reported in addition to a tetradentate ligand based on 1,5-diaminopentane.
When a single synthesis error needs to be corrected, a non-mutagenic primer set corresponding to a sequence in the vector backbone is used in addition to the correcting primer set such that 2 fragments are generated (as if 2 corrections were being made) in order to avoid using mutually annealing primers in a single reaction.
Herein, we describe the rational design of 100 temperature-adapted adenylate kinase enzymes using a multistate design strategy that incorporates the impact of conformational changes to backbone structure and stability, in addition to experimental analysis of thermostability and function.
New potential cancer chemotherapeutic complexes Cu Sn2/Zn Sn2 3 and 4 were designed and prepared as topoisomerases inhibitors; their in vitro DNA binding studies were carried out which reveal strong electrostatic binding via phosphate backbone of DNA helix, in addition to other binding modes viz.
It must be noted that, to account for incomplete sampling, MEDUSA employs a backbone tree while BAMM, in addition to relaxing the assumption of time-homogeneous diversification used in most previous approaches, operates over the empirical phylogeny without any pruning [ 48].
In addition to backbone and side chain molecular weights, grafting density and topology are the major parameters that directly influence graft copolymer micellization.
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