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The Piwi domain of Drosophila Ago1 is a RNase H like endonuclease that cleaves a single phosphodiester bond in the target RNA backbone if it is perfectly complementary to an associated miRNA (Miyoshi et al. 2005).
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If it is a backbone problem, the clueful reps who actually listen to you will escalate to their backbone group.
We've got to transform that, particularly if it is one of the backbones of our industry.
"They had every reason to believe that if it wasn't them, it would be people like them who would have to provide the administrative backbone," Korr said.
Level 3 does act like a backbone and it is an extremely important backbone.
He says to the United Nations on Sept. 12, if this organization has a backbone it is going to stand up to Saddam Hussein, demand inspections for the weapons of mass destruction and remove or destroy them.
If you want a tightly edited, slick choreography of clips with the soundtrack forming the backbone, then it's probably before.
If that backbone snaps, well, it's all over.
Conor Ryan, who was a special adviser to David Blunkett and worked alongside Adonis in the education department, is not surprised to see him displaying backbone: "If he is sure something is right and needs to happen, he is quite prepared to be steely".
Capital is the backbone of our economic system and how it is treated is the backbone of our political one.
It is the backbone on which all successful relationships are built and if the trust is lost the relationship can become irreparably broken.
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