Sentence examples for backbone functional groups from inspiring English sources

The Rosetta enzyme design protocol starts with minimalist active site descriptions consisting of transition state models surrounded by disembodied side chain and backbone functional groups positioned optimally for catalysis, so called theozymes [5].

The first step in the enzyme design process is to model the reaction transition state(s) and decide on a set of idealized active site descriptions consisting of disembodied side chain and backbone functional groups surrounding the transition state in positions optimal for catalysts.

There is also significant cross reactivity, which depends on the chemical nature of the glycan backbones and functional group modification of the sugar components.

Each backbone structure has similar functional groups and is subject to similar metabolic modifications (Wang et al. 2004).

It is well known that osmolytes induce protein folding due to solvophobic effects on peptide backbone, and the fact that protein backbone comprises the most numerous functional groups of proteins, osmolyte-induced conformations result in native-like functional species [21].

11,  12,  17 1 These LCOs were chosen as their molecular composition varies in anionic substitution patterns and in backbone rigidity, as well as in terminal functional groups extending the thiophene backbone.

Also, the nature and quantitative contributions arising from functional groups or backbone chain have been assessed.

Product design through varying the structure of the amine compound, such as backbone structure and presence of functional groups, appears to be a promising polymer engineering pathway.

Through functionalization of both diene and dienophile on the double-stranded siloxane backbone with ternary n-alkyl functional groups acting as chain mobility control, the effect of chain mobility and chemical structure on self-healing and mechanical properties were elucidated.

Thus, it indicates that use of the above functional groups, as backbone moiety is helpful for designing inhibitors active against EGFR.

The copolymers (PLS2) have ester and amide functional groups in the backbone, as well as pendant free hydroxy functional groups.