Exact(2)
The Rosetta enzyme design protocol starts with minimalist active site descriptions consisting of transition state models surrounded by disembodied side chain and backbone functional groups positioned optimally for catalysis, so called theozymes [5].
The first step in the enzyme design process is to model the reaction transition state(s) and decide on a set of idealized active site descriptions consisting of disembodied side chain and backbone functional groups surrounding the transition state in positions optimal for catalysts.
Similar(58)
Heterologous expression of mtr-miR159b-amiR constructs in tobacco showed that the backbone is functional and mediates an efficient gene silencing.
An lncRNA may have a conserved backbone and/or functional domains but have varied structure in different species, making the determination of the accurate structure of the full lncRNA difficult and sometimes unnecessary.
There is also significant cross reactivity, which depends on the chemical nature of the glycan backbones and functional group modification of the sugar components.
Brodribb, T. J. Xylem hydraulic physiology: the functional backbone of terrestrial plant productivity.
The PNIPAM-g-PNIPAM hydrogels indicted further accelerated shrinking kinetics than functional backbone hydrogels.
To address this challenge, zwitterionic Poly(sulfobetaine 3,4-ethylenedioxythiophene) (PSBEDOT) that contains EDOT backbone with sulfobetaine functional side chains were developed in our previous study.
The chemical structures of the resulting poly(1,6-heptadiyne)s were characterized by various instrumental methods such as NMR, IR, UV-visible spectroscopies and elemental analysis to have the conjugated polymer backbone systems with functional substituents.
In previous gaming generations, these mid-range games formed the functional backbone of gaming.
Aromatic molecules or the molecules with aromatic groups can be embarked on the debunching and solubilization of CNTs using nucleic acids and amphiphilic peptides based on the π-π stacking interactions between the CNT surface and aromatic bases/amino acids in the structural backbone of these functional biomolecules.
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