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The administration of appropriate definitive treatment in patients with PA-BSI, even when delayed, remains the backbone for improving clinical outcomes and should be combined with routine infection control measures to further reduce morbidity and costs.
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Modification of these molecules with efficient backbone moieties for improved stability and potency, protecting and buffering them with delivery vehicles, and using scaffolds as reservoirs of delivery is at the frontier of current research.
The benefits of using caches for reducing traffic in backbone trunk links and for improving web access times are well-known.
It has also done vital work in establishing sustainable public health systems that will be the backbone of improving health care -- especially in Africa for generations.
The results reveal that the introduction of the conjugated side-chain with an electron-deficient group to a polymer backbone is an effective approach for improving the performance of the photovoltaic materials.
One avenue for improving activity with crXNA molecules would be through the use of alternative backbone chemistries that may be more tolerated by Cas9, or through evolution of Cas9 to accommodate these molecules more efficiently by improving the conformational changes of the complexes.
The interconnected network backbone and rich porosity in NP-TiO2/Co3O4 composite effectively buffers the volume change as well facilitates the diffusion of Li+, while the combination of Co3O4 is favorable for improving the capacity of the TiO2 sample.
For improving.
We employed a combination of molecular modelling and crystallographic structure analysis to design renin inhibitors lacking the extended peptide-like backbone of earlier inhibitors, for improved pharmacokinetic properties.
In principle, CPD can easily generate hundreds of thousands of sequences for a single backbone template, potentially improving the exploration of sequence space in cases where experimental data is rare.
In a quest for improved therapies, investigators have adopted various strategies to intensify treatment, building on the CHOP backbone, or have developed nonanthracycline-based alternatives.
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