Sentence examples for backbone disorder from inspiring English sources

We probe the robustness of the two hydrophobic clusters in the folding transition state, discuss how local backbone disorder in the native-state can lead to non-classical ΦM‐values (ΦM > 1) in the rate-determining loop 1 substructure, and conclusively identify mutations and positions along the sequence that perturb the folding mechanism from loop 1-limited toward loop 2-limited folding.

In aqueous solution, this 140-residue protein adopts a dynamically disordered backbone conformation, but its Cα chemical shifts also have been interpreted as being indicative of a slight propensity to adopt α-helical torsion angles for several sections of its backbone.

This dramatic decrease in mobility is believed to originate from twisted PBTTT backbones and side group disorder due to intercalated fullerenes.

This is mainly because side-chains are not as stable as backbones, and they are more likely to have disorder problems than are backbones in crystals [ 22].

This is the backbone of the Iodine Deficiency Disorders elimination effort.

Nucleotides 20 21 are disordered, but the backbone was modelled to help view the RNA structure and is indicated in grey cartoon style, as is also the last modelled phosphate at the 5′-end of RydC.

A planar backbone conformation minimizes the scope for structural disorder, enables chains to pack closely with small π−π stacking distances of 3.6-3.8Å 3.6-3.8Ås to reduce the torsionandcontendstoon to the reducenizathen energy for electorsionalsfer.

Although predicted disordered regions correlate well with experimentally determined backbone dynamics, detailed prediction of conformational subtypes requires a more sophisticated description of disorder.

Molecular dynamics simulations revealed that NQTrp destabilizes the inter-chain backbone hydrogen bonds and increases considerably the structural disorder within the Aβ oligomer.

The 1500 cmodemode is proposed to originate from disordered PBTTT C=C thiophene rings, probably because of fullerene intercalation-induced disorder among the alkyl side groups causing twisting of the backbone thiophene rings and greater paracrystalline disorder.

We observed poor electron density for the loop backbone atoms in both structures, suggesting that the loop is disordered, as would be expected.