Sentence examples for backbone at a position from inspiring English sources

DNA strand has been cleaved at the phosphodiester bond to leave sugar-phosphate backbone at a position 5' of AP active site as the reference ligand for docking.

However, neither the backbone at position 268 nor that at position 264 appears to make contact with the galactopyranosyl ring of NPG.

This is in strong agreement with the crystal structure of the GR DBD IL8 κBRE structure, as the GR DBD makes two close interactions (2.7 Å) with the DNA backbone at this position (Fig. 5f).

Although the results are somewhat ambiguous, they imply that the backbone at the position of Gly268 might interact with bound sugar and that the moderate decrease in affinity exhibited by mutant G268A may be due to the steric hindrance.

Firstly, the reduction of the side chain in contact with the phosphate backbone at this position facilitates the D-box tilting in direction of the dimerization interface with the partner (compare the respective regions at the Figures 4-A to D).

In addition, the mutation V32P within the signaling motif-N (at a position not directly involved in H-bonding) also resulted in slightly reduced activity, presumably due to effects on the backbone conformation and/or flexibility of the β-strand.

It has two sets of sn1 and sn2 chains at two different glycerol backbones attached to two phospho groups that are further connected to another glycerol backbone at 1' and 3' positions; no head group is specified.

Biosynthesis of CS involves sulfation of the sugar backbone at various positions, which generates diversity in their oligosaccharide sequences.

7α,25-OHC contains three hydroxyl groups attached to its steroid backbone at positions 3, 7, and 25 (Fig. 1).

Protein flexibility: to reflect the mobility of the protein's backbone at the mutated positions, we used the B-factors of the crystal structure (F8).

Docking studies suggested π-stacking interactions with Trp641 as a potential cause, and suggested that shifting the amide bond of 7 closer to the catechol moiety might facilitate hydrogen bonds between the inhibitor and the protein backbone at amino acid positions 642 and 644 (see Figure S4 in the Supporting Information).