Sentence examples for backbone analysis from inspiring English sources

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Serrano et al.[ 6] have shown that the backbone analysis is more successful in extracting meaningful links from dense networks than more conventional reduction algorithms, such as global thresholds, in a variety of data sets, but not to biological data.

While backbone analysis (i.e. the combination of MLST, rMLST and whole genome sequencing in this case) accomplishes phylogenetic positioning, its combination with virulence profiles provides a more textured picture of evolution, and enabled us to propose this alternate mechanism of pathogen emergence.

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Structural risk minimization is a machine-learning framework that addresses the issue of over-fitting by providing a backbone for analysis as well as an impetus for the design of better learning algorithms.

A comparison of WT and hBChE variants by protein backbone rmsd analysis revealed unusual features.

We will indicate this approach as backbone stability analysis since it focuses only on core genes order.

During the workflow, backbone flexibility analysis was done using rigid-body ensemble docking with multiple structures derived from NMR, while the ZDOCK option for sampling at 6-degree rotational steps was used to obtain the decoys.

In addition, it was possible to carry out a full backbone relaxation analysis of AR1−AR4 of IκBα, and the results reveal multiple time scales of motion centered around the binding interface in the complex with NF-κB.

The finding of mucin O-GalNAc type glycans was supported by the prediction of potential O-GalNAc glycosylation sites on the protein backbone by analysis of the AFP structure by molecular modelling.

The interactome served as the backbone for subsequent analysis of the microarray data, which was carried out using both previously-described and our own newly developed analysis toolsWe thus present a multifaceted analysis of the global gene expression response to dioxin exposure utilizing novel tools of network analysis.

A three-step approach forms the backbone of our analysis: (i) self-alignment of the genomic sequences, (ii) clustering of the resulting matches, and (iii) multiple alignments of each cluster to build a consensus (Figure S1).

We used the published alignments [ 5, 7] as backbone for our analysis.

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