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A PDPA derivative with a long alkyl side chain connected directly onto the backbone (1) was synthesized and compared to a corresponding polymer with a silylene linkage between the side chain and the backbone (2).
1H NMR titration experiments carried out in DMSO-d6/CDCl3 (15/85, v/v) demonstrated that the short oligo aryltriazole)s backbone 1 could not bind halide anions unless that amide H-bond donors were incorporated at the termini of the oligomer.
Modification of proteins can range from the addition of a small chemical moiety such as phosphate to the addition of peptides like ubiquitin and SUMO or the covalent cleavage of peptide backbone (1).
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Only small perturbations to the backbone, 1 2 Å, were needed to entirely mutate the core.
A series of rigid backbone 1,8-anthracene-linked bis-oxazolines (AnBOXes) have been designed, synthesized, and evaluated in the catalytic asymmetric aziridination with [N- p-toluenesulfonyl)imino]phenyliodinane (PhINTs) as a nitrene source.
Based on quantum chemical calculations, we evaluated the interaction energies between several halobenzenes and the oxygen of N-methylacetamide, representing the carbonyl-function of the protein backbone [1, 2].
This deal signals another direction for Badoo's growth: as a backbone, B2B provider for other social networks.
This led to further investigation into the chain stiffness of the copolymer backbone [28, 29, 30].
Feed ratio/composition studies and 13C NMR confirmed the strictly alternating sequences in the backbone [24].
The third stage (> 400 °C) involves the process of decomposition of the polymer backbone [50].
Branched copolymers were obtained by grafting polyacrylamide (PAA) chains onto dextran (D70) backbone [26].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com