I try to step back to a meta-perspective in the hope of achieving a clearer-headed view, but the wide-angle picture becomes even more chaotic.
The surviving subpopulations either diverged into separate species and lineages or channeled their TE-produced mutations back to the meta-population by crossbreeding.
Nevertheless, the subpopulations that survive can become the treasure troves of pre-screened mutations (beneficial, neutral and slightly harmful), which can be transferred back to the meta-population by crossbreeding.
Small populations are much more vulnerable to extinction than the large ones [ 28], but those which survive are likely to become repositories of multiple pre-screened mutations that can be carried back to the meta-population or exchanged between different subpopulations by crossbreeding.
To facilitate the visualization of the QTLs and meta-QTLs and the shift back to markers, the QTLs and meta-QTLs were projected on a virtual physical map composed of microsatellite markers corresponding to those used to build the IR64xAzucena SSD genetic map (Ahmadi et al., unpublished data).
We aimed for a representative sample of the literature from each domain and, in particular, for the current multi-domain meta-analysis to link directly back to previous seminal reviews or meta-analyses of individual behavioral domains.
"The APIs have come a long way, and we are taking advantage of them to connect meta data back to our platform," says Mahoney.
And Louis-Dreyfus's Seinfeld co-stars aren't doing too badly, either: Seinfeld is an elder statesman of the US comedy community and David's follow-up hit, Curb Your Enthusiasm, extended even to a Seinfeld reunion, which Louis-Dreyfus describes as "very meta, like going back to your high school reunion – but having a good time".
For formal direct comparisons across domains and to link the present unified meta-analysis directly back to the literature, studies were re-selected from key reviews (Binder et al. 2009; Noonan et al. 2013) and supplemented, where necessary, to exceed a minimal sufficiency for meta-analysis of each domain.
