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Assembly and maturation of podosomes maintain the extending cell margin, but in order to allow the progression of the leading edge, podosomes need to release their attachment to the substratum and disassemble at the back of the cluster.
As the leading edges of migrating DCs macrophages and osteoclasts protrude, new podosomes form at the front of an existing cluster to sustain the extending lamellae while podosomes at the back of the cluster disassemble to allow translocation (Fig. 1B, Supplementary video 1).
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The ball came back off the cluster of bodies and what happened next from Arnautovic epitomised Stoke's confidence.
When the broadcast was over, she walked back to the cluster of cubicles where her staff sits and scrawled an apology on the whiteboard: "I'm sorry about tonight's show".
Similarly, in the case of migration of the lateral line primordium, CXCR7b expression at the back of the cell cluster was suggested to be responsible for reduction in the level of CXCL12a at that location and to contribute to the generation of a chemotactic gradient despite the uniform expression of cxcl12a RNA [16].
Trailed by an entourage, Lagerfeld — a line leader if ever there was one — made his way, finally, from the back of the auditorium to a cluster of armchairs onstage.
Results indicate that the slender mast arm section is critical in flow separation and vortex formation on the back side of the signal cluster backplates.
The three objects together were themselves flung by gravitational recoil back into an outer region of the cluster.
The back of the device is a dense cluster of ports, and softly shifting the computer around on the desk was enough to trigger the lit-up port guides that will help you guide cords into their proper receptacles.
These advancements haven't made it across town from Seoul National University to the Garwol-dong neighborhood, where artificial limbs are handcrafted in the back of shops clustered together on a single street.
To find them, one must look where the housing stock is very old and tightly clustered, where the back of the lot would have been a viable real estate holding for a 19th-century property owner.
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