Sentence examples for back of the active from inspiring English sources

This motion in the apoenzyme (apo) form is highly correlated with another small loop on the back of the active site and also stabilized with ligand binding.

Inspection of the homologous c-Abl kinase domain structure  [76] shows that Ile638 in DDR2 is located at the back of the active site cleft, in the loop connecting helix αC to strand β4 (not shown).

Superposition reveals that the O6 carbonyl group of diprophylline occupies the same position as the carbonyl oxygen of STZ (positional shift = 0.35 Å), and accepts a similar hydrogen bond from N δ2 of (the conserved) Asn396 at the back of the active site (Fig. 2A and B).

It is also reassuring that these mutations are contextually dependent, meaning that mutations at the very back of the active site (at position 83) are not effective unless they are present with mutations closer to the front of the active site (at positions 86, 146, or 156).

Loss of TG2 could not be compensated by add back of the active exogenous enzyme into the culture system, suggesting a regulated export of TG2 to the cell surface and binding to its cell surface-binding partners, such as syndecan-4 and FN, in order for it to function appropriately.

The reason is LTE-LBPS-Merge determines the sleep cycle length based on the estimation of data accumulation instead of passively getting back to the active mode for each packet arrival as the contrast schemes do.

DOI: http://dx.doi.org/10.7554/eLife.06181.012 Consistent with the results presented above for R166, the presence of R166 has virtually no effect on the rate advantage from adding Mg2+ back to the active site, regardless of which other residues are present or absent.

Comparison of the architectures of BAU-bound and 5-FU bound monomers of hUPP1 reveals that substantial structural changes are restricted to a single loop region toward the back side of the active site.

The differences are even less comparing BAU-bound and 5-FU-bound enzymes, with structural differences limited almost exclusively to a loop lining the back side of the active site pocket (Figure 1, magenta highlight).

In other words, they were learning without being aware of it.The PET scans revealed that the cuneus a small structure at the back of the brain was active during both the four-hour training period and subsequent REM sleep, but not in any other stage of sleep.

At around 60 milliseconds, only early visual cortex in the back of the brain was active (image at left).