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Animal experiments have demonstrated that baboons challenged with a lethal dose of endotoxin had a greater survival chance when corticosteroids were initiated within the first 4 hours, even though delayed treatment was associated with better survival rates than controls [41].
A significant inflammatory response, including secreted TNFα, is observed in baboons challenged with anthrax, although the contribution of toxin to this response has not been determined [62].
That thrombin-dependent APC generation mediates protective effects in sepsis models was convincingly shown by direct infusion of APC into baboons challenged with Escherichia coli [ 31].
Using human oligonucleotide microarrays, we have explored the temporal changes of gene expression in the lung of baboons challenged with sublethal doses of E. coli.
Oligonucleotide microarrays were used to study the time-course of gene expression in the lung of baboons challenged with E. coli.
Animal experiments have demonstrated that baboons challenged with a lethal dose of endotoxin had a greater survival chance when corticosteroids were initiated within the first 4 hours, even though delayed treatment was associated with better survival rates than controls [ 41].
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In a baboon model challenged with a lethal dose of E. coli, the monoclonal antibody C6B7 directed against FXIIa improved survival with higher blood pressure.
and challenged with cocaine.
Because baboons can become aggressive when challenged, they are often killed by farmers for being pests.
Notably, a vaccination schedule of four doses of 1600 μg peptide/nostril in combination with cholera toxin as adjuvant once a week was able to eradicate amoebic infection in all baboons by the 51st day after intracecal challenge with trophozoites.
"In olive baboons, friendships with females can be much more important than political alliances with other males".
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CEO of Professional Science Editing for Scientists @ prosciediting.com