Sentence examples for axis pathway from inspiring English sources

Exploitation of TGF-β effectors and their cross talk with the androgen axis pathway will provide new insights into mechanisms of resistance of the current antiandrogen therapeutic strategies and lead to generation of new effective treatment modalities for CRPC.

Our recent findings further suggest that a novel class III PI3K-ARF6 axis pathway mediates TLR9 immune responses by regulating the cellular uptake of CpG ODN.

However, the genetic risk conferred by the HPA axis pathway for the comorbidity of depression, T2D, and MetS is expected to be stratified in patient groups and to correlate with sub-phenotypes of T2D, MetS, and depression.

Altogether, the gastric inflammation, the hyperactivity of HPA axis, in combination with the anxiety- and depression-like behaviors in female IAA-treated rats suggest that gastric inflammation has a gender-related impact on psychological behaviors via neuroendocrine (HPA axis) pathway.

Our results show that gastric inflammation leads to anxiety- and depression-like behaviors in female but not male rats via the neuroendocrine (HPA axis) pathway, suggesting that the GI inflammation can impair normal brain function and induce changes in psychological behavior in a gender-related manner through the GI-to-brain signaling.

To investigate the impact of inhibition of PI3K/Akt/mTOR axis pathway on the chemosensitivity of canine tumours, we evaluated the effects of the combination of the class I PI3K pathway inhibitors and Doxorubicin on the viability of canine SB and REM cells and utilized the Bliss additivism model to analyze the effects.

Interaction between childhood trauma and genes belonging to the HPA axis pathways have already been explored for depression and psychosis, but not yet for BD (Uher 2014).

This study presents compelling evidence that sox9a axis pathways orchestrate the supporting cell-dominated transition from ovary to testis.

This co-morbidity is the evidence for the existence of GI-brain axis which consists of immune (cytokines), neural (vagus nerve) and neuroendocrine (HPA axis) pathways.

These results were consistent with the in vivo histological observations that the sox9a axis pathways increase ECM production and mesenchymal morphological transformation of gonadal cells.

The activities of the three GI-brain axis pathways through which gastric inflammation may modulate the brain function and behavior were also evaluated.