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We further show that slower stem-cell cycling could be due at least in part to fine-tuning along the distal proximal axis of expression of the cell cycle regulator CYE-1, consistent with a previously identified motif in the germ-line gene regulatory network whose potential significance is highlighted by our approach.
We further showed that slower stem-cell cycling could be due at least in part to fine-tuning along the distal proximal axis of expression of the cell cycle regulator CYE-1, consistent with the presence of a previously identified motif in the germ-line gene regulatory network whose potential significance is highlighted by our approach.
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Axis of evil, expression used to describe the bellicose tendencies of Iran, North Korea, and Iraq in the early 21st century.
Because Carabelli development is not associated in our sample with differences in square root tooth area, we are confident that variation in relative intercusp distance, measured by a ratio using this size variable in the denominator, along an axis of Carabelli expression will be driven primarily by differences in intercusp distance.
The second axis explained 15% of expression variability and separated the samples according to their follicular stages.
The first axis explained 52% of expression variability and separated the two follicular compartments (O and GC).
However, when we compared the Y-axis of the expression space generated without the hNTI cell signature genes with the ESTIMATE scores, we observed a striking and very significant correlation (R = 0.83, P-value <2.2 × 10-16; Figure S7D in Additional file 1; for correlation with other axes and an equivalent analysis for cell lines see Figures S7 to S9 in Additional file 1).
It is important to keep in mind that each axis of a gene expression space represents an independent source of variance, corresponding to different underlying gene expression patterns.
There are several models to describe how blastemal cells arising on the PD axis derive their levels of expression after amputation.
Histogram (gray, left y-axis) and kernel density estimates (blue, right y-axis) of co-expression scores with known complex I genes.
In the dorsoventral axis the expression of regional transcription factors needs to be considered in respect to the rostocaudal region.
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