Sentence examples for axis in specific from inspiring English sources

Collectively, these studies indicate that MAGL is the primary hydrolase responsible for terminating 2-AG signalling in the CNS and that chronic 2-AG overload desensitizes the 2-AG-CB1R signalling axis in specific brain regions, leading to functional and behavioural antagonism of the eCB system.

One of our main findings was the detection of p14ARF promoter silencing as a potential cause of deregulation of the p53-MDM2-p14ARF signaling axis in a specific subgroup of CRCs.

The cause and pathophysiology of FMs is unclear; pathophysiological hypotheses include impairment in the functioning of the hypothalamic-pituitary axis and alterations in specific neurotransmitters such as substance P, N-methyl-D-aspartate, noradrenaline (norepinephrine) and serotonin (5-HT).

Apostolaki et al. demonstrated that the development of intestinal inflammation in the TNFΔare mouse model is critically dependent on β7 integrin-mediated T-lymphocyte recruitment, while the function of the CCL25/CCR9 axis in T-cell specific mucosal recruitment appears dispensable in this model [30].

Coupling and decoupling along this axis has been implicated in specific types of memory (Kensinger & Schacter, 2006).

We show that several of these substances also interfere with multiple targets at various levels of the HPT axis in a tissue-specific manner.

Our results, together with recent findings, emphasise the importance of the CXCL12/CXCR4 signalling axis in the organ-specific patterns of metastasis.

The dendrites of individual MBON types and the terminals of dopaminergic neurons (DANs) intersect the longitudinal axis of KC axon-bundles in specific compartments along the lobes.

Unraveling the complex characteristics of the hyaluronan/RHAMM/CD44 signaling axis in fibrosarcoma may reveal specific targets of pharmacological interventions.

Collectively, these data indicate the important role of the IP-10/CXCR3 axis rather than the TARC/CCR4 axis, in the recruitment of specific inflammatory cells into the lung during pulmonary inflammation in lupus-prone mice.

The specific involvement of the CXCR4/CXCL12 axis in cell proliferation, and organ-specific metastasis has been partially addressed and remains controversial in some tumour systems, including NB [13].