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It is not difficult to imagine Europe after a British withdrawal: a French-German axis in control, Russia empowered, America bypassing a now-weakened Britain, pro-EU Scotland threatening once again to leave the U.K. and England turning inward as Euroskeptics convince themselves that Britain always is strongest when alone.
(F ) Quantification of P6 GluR2 immunofluorescence intensity (left axis) and P15 GluR2 puncta number per IHC (right axis) in control and Mafb CE cochleae.
(K ) Quantification of GluR2 immunofluorescence intensity at P6 (left axis) and GluR2 puncta number per IHC at P15 and adult (right axis) in control and Mafb CKO cochleae.
To investigate the relative effects of disruption of astral microtubules and F-actin on spindle orientation, we measured spindle angle (relative to the x/y axis) in control and drug-treated embryos.
To delineate distinctive role of the components of α5β1 integrin-EGFR axis in control of epidermoid carcinoma cell proliferation, we performed individual inhibition of α5β1 and EGFR via genetic and phamacological methods, respectively.
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These results together highlight an essential role of the IL-25/Th2 axis in controlling tumor progression and tumor metastasis in breast cancer, suggesting that it may serve as a novel target for treatment of metastatic breast cancer.
Expression of E2f (Table 1) is associated with the self-renewal of murine trophoblast stem cells [29], the expansion of stem cells in the columella and lateral root caps of Arabidopsis [30] and with poor prognosis in prostate cancer [31] Recently, genomic profiling indicated the functional role of the Rb-E2F axis in controlling quiescence in adult murine hair follicle bulge stem cells [32].
These rare manifestations of genetic disease together confirm the importance of the PHD-VHL-HIF axis in controlling Epo expression and thus red cell mass in humans.
19 In subsequent decades, the role of the hypothalamic-pituitary axis in controlling testosterone production, namely through the secretion of GnRH, was elucidated.
(H) Quantification of the cell division time (from NEBD to chromatin separation, time/min, Y-axis) in control (n = 40), AurkB-OE (n = 24), AurkC-OE (n = 52), siAurkB (n = 50), and siAurkC (n = 42) groups (X-axis), each dot represents one embryo in the group, and the bar and whiskers indicate means and SD, *P < 0.05, **P < 0.01, ***P < 0.001.
In contrast, some F2 embryos displayed longitudinal divisions, thus altering the radial symmetry of the embryo axis observed in control plants.
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