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In indeterminate inflorescences the growing region of the axis functions for extended periods so that as the older flowers mature and set fruit near the base of the inflorescence axis, younger buds develop and continue to expand into flowers at the apex.
However, the molecular mechanism(s) by which the Snail-MMP signaling axis functions in tumor neovascularization remained unknown until now.
If MMP-9 is playing a major role in the activation of Neu1 sialidase in complex with EGFR as our data suggest, logistically Snail in inducing MMP-9 in ovarian A2780 cancer cells may be the molecular mechanism(s) by which the Snail-MMP signaling axis functions in tumor neovascularization.
Collectively, the results demonstrate that the Dvl-Rac-Rho axis functions through regulating G3BP activity.
MR is an important regulator of HPA axis functions and deletion of MR results in increased serum CORT levels [ 37].
Thus, our data imply that p33ING1 CSIG axis functions as a novel pro-apoptotic regulator in response to DNA damage.
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Conclusions: SGA subjects have pituitary-gonadal axis function that tends toward hypogonadism.
If unrecognized and untreated, impaired HPA axis function may result in a lethal outcome [33, 34].
This study attempted to assess the relationship between patient characteristics and HPA axis functioning using a neuroendocrine challenge test.
As an indicator of HPA axis function, serum corticosterone levels were determined by enzyme immunoassay at various time points.
Assessment and treatment of adrenal axis function in critically ill pediatric patients with oncologic disorders have not been well elucidated.
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