Sentence examples for axis for the development of from inspiring English sources

The importance of the central PRLR-STAT5 signaling axis for the development of the secretory gland has been elucidated in mice by knocking out the genes encoding the components of the pathway.

Therefore, the data suggest that both functional LTβR and TNFR2 axis are required for the development of microvascular pathology resulting in fatal ECM.

Indeed, Sims et al (2010) recently argued a predominant role for the HMGB1 RAGE axis in the development of inflammation and cancer.

Targeting the functional cross-talk between the TGF-β signaling effectors with the androgen axis supports the development of novel therapeutic strategies for treating CRPC with high specificity and efficacy in a personalized-medicine approach.

Recent findings suggest an important influence of the GH1/IGF1 axis in the development of breast cancer.

Dysregulation of the inflammatory axis predicts the development of insulin resistance and type 2 diabetes mellitus.

PI3K pathway inhibition is an attractive axis in the development of targeted treatments in GBMs.

To date it is not known, if any of such disruptions in the genes of the IL-17/IL-23 IL-17/IL-23 IL-17/IL-23e risk for the development of sepsis, probaxisity of surviving sepsis or areeratinfluencing immune surveillance afthe riskvery form sepsis.

The PI3K/AKT/mTOR signaling axis provides a direct link for the development of prostate cancer.

Manipulation of the T-bet axis may provide molecular targets for the development of new strategies in the prevention and treatment of insulin resistance and type 2 diabetes.

Interestingly, several of the stimuli are also released in response to LOX-1 activation such as endothelin-1 and TNF-α and oxLDL itself increases LOX-1 expression, suggesting that the LOX-1 axis composes a vicious cycle for the development of atherosclerosis [ 15, 29, 36, 44].