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For this purpose, we quantified three axes: cell type (x-axis), time of development (y-axis), and pseudo-potential function (z-axis, see methods for more details).
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGFβ) family that regulate various biological process including embryonic axes, cell fate determination, proliferation and apoptosis in both invertebrate and vertebrate model systems.
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Orientation of long axes and cell division were biased similarly in zebrafish lens epithelium, suggesting that cell geometry correlates with cell-division orientation.
Regulatory interactions between FGFR4 and NFκB signaling pathways have not previously been reported, although both pathways represent major axes of cell signaling.
The vacuolar status of cells in embryonic axes and further cell vacuolation in elongating cells are of primary importance, because the water entering vacuoles produces additional pressure on cell walls, thus favouring elongation.
In a zebrafish e-cadherin mutant, the long axes and cell-division orientation were shifted more longitudinally.
This coordination of the polarization axes between cells in the tissue is critical for development and function of organs (Simons and Mlodzik, 2008), and is referred to as planar cell polarity (Sepich et al., 2011).
A firing rate vector was constructed by arranging the firing rate maps into a 3D matrix with the 2 spatial dimensions represented on the x- y-axes and cell identity on the z-axis.
Sequentially tilted, energy-filtered (slit width 20 eV) images of individual cells were collected automatically using either the UCSF tomography [58] or Leginon software packages [59] in 2° increments up to +/−∼56 60° along either one (36 cells) or two (16 cells) axes [19] at 18,000× magnification, resulting in a CCD pixel size of 1.2 nm.
The C2 units lie parallel along the cell axes, causing a distortion of the cell from cubic to tetragonal.
All axes and unit cell guides are deleted.
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