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The phrase "aware of the substantial" is correct and usable in written English.
It can be used when discussing knowledge or understanding of significant matters or issues.
Example: "The committee is aware of the substantial challenges facing the organization this year."
Alternatives: "conscious of the significant" or "mindful of the considerable".
Exact(7)
A person is aware of the substantial likelihood of displacement through their order.
The reporting radiologist should be aware of the substantial secondary tissue damage caused by in-driven fragments of bone and teeth, which themselves become secondary projectiles (Figs. 12a c and 13a, b).
If we, as members of the "startup community" and more broadly as a society, want to see more money being invested in more UK startups, there's only one way to do it: make the people who have capital aware of the substantial returns that are available from investing their capital in UK startups, full stop.
Employers may not be aware of the substantial burden that opioid abuse imposes on them.
If health is to retain prominence in the post-2015 global global health strategists need to be aware of the substantial difference in context that the sustainable development agenda represents.
From this finding, we suggest that nursing home leaders, directors and ward leaders should be aware of the substantial differences between dysfunctional teams and real teams; and should support the development of real teams within their wards, which, our study finds, will improve the quality of care for their nursing home residents.
Similar(52)
If they are not aware of this "substantial concomitant use of prescription drugs and dietary supplements" [ 24], harmful interactions of drugs with herbs or supplements cannot be prevented.
GPs need to be aware of this substantial minority of smokers who present in consultations with them and are very negative about stopping smoking.
The drug's sales will be suspended entirely in Europe, while patients in the United States will be allowed access to the medicine only if they and their doctors attest that they have tried every other diabetes medicine and that patients have been made aware of the drug's substantial risks to the heart.
However, we believe that it is useful for countries at different stages in the development of smoking cessation policies to be aware of the likelihood of substantial divisions of opinion among GPs and that these may be based on more fundamental values than a specific scrutiny of the evidence on particular types of medication.
The guidelines recommend that ADHD medication should not be prescribed to pre-school children for the long term.nor in isolation from other therapeutic interventions, without consultation But the association said it was aware of a substantial increase in the number of children aged under six, and in some cases as young as three, being prescribed ADHD drugs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com