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Perhaps, the most early awaited combination data is RECORD II that compares bevacizumab and everolimus vs bevacizumab and interferon.
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Given the vast repository of individual models in the literature and in online databases that await combination and validation, we have shown that our methods have great potential for application in systems biology.
Whether the Rodarte sisters can tame their intense vision and intricate handwork in their new line for the retailer Target makes that project the most eagerly awaited high/low combination of this fashion season.
However, completion of multicountry phase III trials being conducted by the Drugs for Neglected Diseases Initiative (www.dndi.org) is eagerly awaited before the combination can be considered as an alternative.
Results for aflibercept plus other chemotherapy combinations are awaited from trials in several tumour types, including metastatic prostate cancer.
Further studies in different settings or with different triple single-pill combinations are awaited to shed more light on this field.
In the meantime, MR studies after the B-R combination are eagerly awaited.
Data on specific combinations are eagerly awaited.
Phase II trial data is awaited as second line therapy in combination with pemetrexed.
Since adverse events resulting from therapy with CTLA-4 blocking antibodies in murine models are not predictive of adverse events in humans, definitive characterization of the tolerability of the combinations awaits further testing in the clinic.
Short-term markers of future benefit would be clinically useful, and information on effective treatment combinations or sequences is awaited.
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