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This led us to give some toxicity only to responder-patients avoiding to induce toxicity in non-responder patients (equal or less than 8 cycles).
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We tested a new schedule of injections designed to avoid tolerance and to induce neurobiological changes relevant for depression.
To avoid the plasticity to induce the unphysiological state where a single presynaptic cell fired a postsynaptic cell, the maximal excitatory synaptic weight were set as: <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0006247.e069.PNG" class= inline-graphic"/>.
The results of our previous studies suggest, however, that administration of cationic mannose-free liposomes may significantly enhance the antibody response (15) and should be avoided in attempts to induce self-tolerance.
First, by avoiding an environmental stress to induce the HSR, the cells maintain a healthy cellular physiology.
Specific information on possible referral patterns was avoided in order not to induce bias [28].
Concomitant inhibition of these pathways is however required to avoid molecular crosstalks and to induce massive apoptosis [ 11].
While the majority avoided points traditionally used to induce labour, 13% would use LI 4, 22% SP 6 and 38% BL 31.
This freezing procedure penetrated the bone and induced a defined morphological injury in the underlying brain tissue The midline of the cranium was avoided in order not to induce any damage to the superior sagittal sinus.
This finding not only provides a new approach to induce pluripotency, avoiding tedious genetic manipulation, but also revolutionizes our understanding of molecular mechanisms of reprogramming, raising the possibility to modulating cell fate by simply modifying intrinsic cell signaling pathways alone.
The lower laser powers (up to 0.5 mW) were used to avoid inducing thermal changes to the mineralogy of the iron oxide minerals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com