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The network model was constructed to depict biological mechanisms related to inflammatory responses elicited by exposure to CS in disease-free pulmonary and immune cell types, with a particular focus on avoiding mechanisms of inflammation that are potentially specific to a particular pathological tissue context.
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An essential virulence feature of both enteropathogenic yersiniae and Y. pestis is the ability to block phagocytic uptake to avoid mechanisms of the innate host defense.
33– 34 The rationale for immuno-oncology is the potential to overcome immune escape mechanisms, to achieve long-standing antitumor effects based on the establishment of memory response, and to avoid mechanisms of resistance that occur with treatments that directly target tumors.
Nevertheless, to avoid known mechanisms of resistance, intelligent combination approaches for multiple simultaneous and complimentary therapies must be designed.
We employ this transfusion strategy to avoid additional mechanisms of coagulopathy as the new oral anticoagulants prolong the PTT and INR and, thus, interfere with laboratory monitoring of other coagulation abnormalities.
The use of a repeat visit made it possible to handle the mental symptoms separately and thereby avoiding the mechanism of competing demands.
Once the therapeutic effect of an ADC has been maximized, it is also desirable to prolong these effects by avoiding resistance mechanisms that decrease the duration of ADC efficacy.
The discovery of multiple structural classes of compounds that modulate gamma-secretase activity, instead of inhibiting it, offers the potential promise of avoiding the mechanism-based adverse events observed with gamma-secretase inhibitors.
In these structures, the structural connections are crucial to achieve a favourable distribution of horizontal loads and to avoid out-of-plane mechanisms.
Mechanisms of avoiding conflict through the reduction of unwanted interactions (both face-to-face and through line-of-sight) include spatial and temporal channelling of movement that regulate mobility (Al Huzil 2012), and different forms of seclusion ranging from high fences around residential lots to strict dress code for women (the veil being a symbolic form of seclusion).
The mechanisms of avoiding host digestion remain largely unknown, although some studies suggest that persistence may be due to the failure of phagosome-lysosome fusion [ 3- 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com