The phrase "avoiding immune" is not correct and does not convey a clear meaning in written English.
It may be intended to describe a situation where one is trying to evade or prevent an immune response, but the phrasing is awkward and unclear.
Example: "The researchers focused on avoiding immune responses to ensure the success of the treatment."
Alternatives: "evading immune" or "preventing immune".
These data have direct relevance for design of clinical trials and strategies aimed at avoiding immune responses against a secreted transgene product.
Different types of bacteria face different pressures from the immune system, with those that persist ("hit-and-stay") potentially having to adapt more in order to escape than those prone to short-lived infection ("hit-and-run"), and with commensal bacteria potentially different from both due to additional physical mechanisms for avoiding immune detection.
Intracellular pathogens like Francisella inhibit the innate immune response, thereby avoiding immune recognition and death of the infected cell.
All together, clearance of influenza virus from the lungs is therefore yet another example of the delicate crosstalk between innate and adaptive immune response that emerged through evolution to safeguard the host from infectious threats while avoiding immune pathology to the host.
Regarding drug delivery, patient-derived EVs could be used to package molecules capable of avoiding immune responses.
Two 'emerging' hallmarks: Avoiding immune destruction whereby tumor cells avoid immune surveillance that would otherwise mark them for destruction.
Initial studies suggested that, unlike 'normal' transplants, specific characteristics of stem cells enabled them to avoid immune attack.
This novel treatment approach is based on the observation that tumors avoid immune system recognition by co-opting immune checkpoints intended to prevent autoimmunity.
Currently, to avoid immune system rejection, CAR T cells are made for each patient individually using their own cells.
In particular, iPSCs generated from patient-specific somatic cells provide promise for personalized cell therapy, which could avoid immune rejection and the ethical issues associated with human ESCs.
In order to avoid immune response, in clinical contests, cells would be isolated from the patients who need an implantation (Mandrycky et al. 2016).
