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Rationally designed RNA nanoparticles with defined stoichiometry and high homogeneity have been demonstrated to specifically target tumor cells while avoiding accumulation in healthy vital organs after systemic injection.
By transferring electrons to oxygen or nitric oxide (NO), they help avoiding accumulation of these toxic compounds.
The electronics also precisely match the cycles of alternating current flow during rotation, ensuring that it is net balanced at the end of each shock, thus avoiding accumulation of ionic gradients in the dish (e.g., excess of positive or negative charges at any electrode vicinity).
DAP (6 mg/kg daptomycin every 48 hours) in patients receiving low-flow CVVHDF resulted in showing variability of AUC and avoiding accumulation.
We have developed tenfibgen (TBG) nanoencapsulation technology that allows for delivery of nucleic acids into malignant cells in vivo while avoiding accumulation in normal cells [ 1- 3].
The G1 arrest delays DNA damaged cells from progressing through the cell cycle, avoiding accumulation of mutations and chromosomal aberrations by means of DNA repair or apoptosis.
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One hypothesis for the function of parkin is that it regulates appropriate levels of its protein substrates, avoiding accumulations of aggregate-prone substrates such as α-synuclein, Aβ peptide, and Huntingtin protein.
Unlike whales and ships, sharks avoid accumulation of algae and barnacles thanks to intricate patterns in their skin.
For metabolic steady state, enzyme feedback control has been known to explain why metabolites in metabolic pathways can avoid accumulation.
We show that, unlike in parabolic problems, conservation properties necessitate a coupling of temporal and spatial accuracy to avoid accumulation of spatial approximation errors over time.
HIF-1α signaling limits oxygen consumption to avoid accumulation of harmful ROS and preserve redox balance, and additionally induces a switch to glycolysis to prevent energetic distress.
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