Sentence examples for avoidance of cell from inspiring English sources

Growth promoting pathways can drive either growth or aging, whereas avoidance of cell cycle arrest precludes aging (Fig. 1).

This intrinsic capacity was attributed to expression of genes which lead to avoidance of cell death pathways [ 63].

These results suggest that the sustained anti-tumour effect and regression observed when barasertib is scheduled before selumetinib is likely to be due to an avoidance of cell cycle-mediated antagonism which allowed an increase in cell death.

As avoidance of cell cycle arrest is a common alteration in cancer, agents that are able to induce cell cycle arrest can act as a barrier to cancer and are increasingly used in combination with conventional cytotoxic drugs to improve anticancer efficacy and overcome drug resistance [ 41], thus displaying the potential use of C. sativum root to enhance conventional chemotherapy.

In teleological terms, the prime finality of autophagy is the mobilization of the cell's reserves and hence the conversion of macromolecules into energy-rich substrates that are required for maintaining essential functions, the avoidance of cell death, and the adaptation to stress.

Recent work demonstrates that miRNAs have essential roles in HCC progression and directly contribute to cell proliferation, avoidance of apoptotic cell death, and metastasis of HCC by targeting a large number of critical protein-coding genes.

Aberrant activation of the Ras/Raf-pathway contributes to essential aspects of tumor development and progression such as cell cycle deregulation, avoidance of apoptosis, cell motility and drug resistance and are moreover known to be important for tumor maintenance and cancer cell viability at late stages of tumorogenesis [ 19, 20].

TrkA is the high affinity catalytic receptor for the NGF and it mediates the main effects of NGF, which include cell growth, the formation and regeneration of neurites, and avoidance of programmed cell death [ 39].

There is a multitude of critical steps during the pathogenesis of cancer in which avoidance of programmed cell death assures the progression, and maintenance, of the malignant phenotype (Fig. 1) [ 7, 8*, 9, 10].

Also, easy preparation, long term storage, and avoidance of potential limitations of cell-based treatments shed valuable light on its potential clinical practicality.

In this study we provide the first evidence that the histone demethylase KDM1A is functionally involved in the regulation of the malignant phenotype of medulloblastoma cells by influencing three major hallmarks of cancer cells, uncontrolled cell proliferation, avoidance of apoptosis and migratory capacity.