The phrase "avoid significant interaction" is correct and usable in written English.
It can be used in contexts where one wants to suggest minimizing engagement or communication with others.
Example: "In order to maintain focus on the task at hand, we should avoid significant interaction during the meeting."
Alternatives: "limit substantial engagement" or "reduce meaningful contact.".
In contrast, zosuquidar, a highly specific P-gp inhibitor, which does not interact with other transporters including MRP1, MRP2 and mutant BCRP (R482T) [ 12], has been developed in an attempt to avoid significant pharmacokinetic interactions and therefore allow co-administration of standard dosing of cytotoxic chemotherapy.
Specifically, any new drug should ideally be able to shorten the duration of treatment, avoid significant drug drug interactions with current regimens, treat MDR and XDR TB patients (via a new mode of action), and be cost competitive with current drugs.
The nanowires are well separated one from each other in order to avoid significant influence of dipolar interactions between nearby nanowires.
This helped to minimize stress shielding and subsidence of the cage and allowed optimum interaction of compressive forces at the graft-host interface, which could avoid significant subsidence and result in high fusion rate that our study has confirmed.
Therefore, clinicians should pay attention to other drugs catalyzed by CYP3A, especially those substrates with a narrow therapeutic range such as cyclosporine A, to avoid possible clinically significant interactions with GA [ 82].
To avoid artificial inflation of significant interactions, we filtered out any exon-SNP-meth triplets where the SNP and methylation site correlated with p<0.05.
Based on these results, precaution should be taken in mind to avoid coadministration of these herbs with CsA until a lack of significant interaction in human is proven by appropriately designed clinical studies.
In the presence of statistically significant interaction, the primary effects of variables involved in the interaction terms are not interpreted, in order to avoid erroneous conclusions.
No significant interaction of mutation × BIM treatment was observed.
But Graham had certainly never noticed any significant interaction between Doug and Lindsey.
