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Here, we would like to further explain the experiments performed to avoid possible misinterpretation of the results.
Participants recommended simplification of some of the wording used to avoid possible misinterpretation and provision of additional space to document any issues raised and actions to be taken.
Many of these reactions give apparently positive signals in a variety of p53 assays, and very stringent analysis is required to avoid possible misinterpretation of these responses as a p53-specific B-cell response in human cancer patients.
To avoid possible misinterpretation due to flow cytometry as previously described, the induction of apoptotic cell death by both RTX and GA101 was confirmed by western blot analysis revealing cleavage of caspase 3 and PARP.
To avoid possible misinterpretation, the analysis was performed using a threshold value for skin-floor contact of 44 arbitrary units (a.u, possible range 0 to 255), that is, all pixels brighter than 44 were used.
To avoid possible misinterpretation due to flow cytometry as previously described, we confirmed cell death induction by western blot analysis of PARP and caspase 3 cleavage (on disgregated or entire MALC), determination of cytochrome c realease, Δ Ψm modification and ROS production.
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It also puts forward the need to better characterize the sources of sediment in order to avoid possible misinterpretations.
However, previous knowledge of the electrochemical DNA biosensor surface morphology and of the electrochemical behavior of the drug at a bare electrode is most important to avoid possible misinterpretations.
This result makes it clear that expert knowledge and further additional information (taken for example from Google Street View) are needed in the methods using remote sensing to avoid possible misinterpretations.
To avoid possible misinterpretations it is perhaps also informative to underline that our claims with respect to the norm validity are situated at the psychological processing level.
The differential expression and specific functions of surface and nuclear nucleolin indicate the need to distinguish between these two forms of nucleolin in future studies in order to avoid possible misinterpretations of experimental data.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com