It is tempting to speculate based on the characteristic paucity of TLR and NLR ligands that is a hallmark of H. pylori that the pathogen has evolved precisely to avoid DC maturation, and to thereby promote Treg rather than T-effector responses.
The protein solutions were diluted to an optical density of ∼0.1 at ∼560 nm after maturation to avoid artificially shortened maturation times due to inner filter effects.
After efferocytosis, anti-inflammatory mediators are produced by the APCs mainly DCs whereas the release of inflammatory cytokines is inhibited by avoiding DCs maturation.
BCG is highly similar to MTB in antigenic composition [ 39, 40] and equally efficient at avoiding phagosomal maturation and lysosomal fusion [ 23, 24].
From imaginal moult to the beginning of tests, adults from a given ootheca were separated by sex to preserve their virginity but remained grouped to avoid delaying sexual maturation [47].
While we have assumed throughout our analysis that managers will seek to avoid harvest-induced maturation evolution, some fisheries managers may regard such evolution as desirable under certain circumstances.
Our results suggest that to reliably avoid harvest-induced maturation evolution in lacustrine brook charr, harvest regimes should be designed to limit the harvest to less than approximately 15% of the population's biomass, or restrict harvesting to individuals larger than 50% of the observed maximum length.
One reason for our decision to control for IQ, well knowing that there is a current controversy about this topic, was the fact that we partly wanted to avoid issues concerning late maturation of the frontal lobes and the close overlap between the constructs of EF and fluid intelligence [ 50, 51].
These women were also given two 12 mg doses of Betamethasone with 24-hour intervals to accelerate fetal lung maturation, avoiding tocolytic agents administration.
Cyclic glucans modulate maturation of BCV to avoid fusion with lysosomes [23], while VirB is required for the late BCV maturation events corresponding to sustained interaction and fusion with the ER [4].
