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To avoid allocation bias, concealed allocation using a sealed envelope was employed in this study.
To potentially reduce trial duration and to avoid allocation of patients to an inferior treatment, an interim analysis will be performed.
For example, it has been recommended that CEA be conducted from a societal perspective, and that a lifetime horizon be employed, since only these approaches avoid allocation biases that may be introduced by a narrower approach.
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Judicious use of adaptive designs may increase the information value per resource unit invested by avoiding allocation of patients to non-efficacious/unsafe therapies and allowing stopping decisions to be made at the earliest possible time point.
By avoiding allocations, the operating report can be based on accurate, objective data on the cost center's consumption of resources during a period.
To avoid biased allocation, randomisation is undertaken by central allocation using a computerized random number generator at the Internet Data and Information Center for Medical Research (INDICE), provided by the University Hospital Medical Information Network UMINN) in Japan.
The allocation approach demonstrates systematic multiscale process model development to avoid arbitrary allocation assumptions.
To avoid initial allocation conflicts, the order in which RBs are considered within each BS is randomized.
The initial randomization sequence was created after implant surgery once the previously defined LC1 had been met, by means of variable block sizes in order to avoid disproportionate allocation within early loading or conventional loading groups [39].
We chose a cohort design instead of a randomized clinical trial, to avoid the allocation of the infant feeding practices at random and then minimize the ethical considerations and the risk of non compliance inducing at-risk mixed feeding-practices, as previously reported [27], [28].
We cannot avoid resource allocation, and we cannot avoid value judgements.
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CEO of Professional Science Editing for Scientists @ prosciediting.com