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Exact(1)
To calculate, e.g., the average trough concentrations for a set of doses at trough time (evaltime), 3*24 = 72 h, we calculate the statistic of interest, concstat, at each integration step, but we only store it into stats if we have arrived at the time of evaluation.
Similar(59)
The observed steady-state average trough concentration (Ctrough,ss) was 21.3 ± 12.0 μg/mL.
No patient had a high trough infliximab concentration, 17 patients (71%) had medium trough concentrations, and 7 (29%) had low trough concentrations.
Mean trough concentrations after the second ziv-aflibercept dose plateaued and remained at ∼10 mg l−1.
Mean trough concentrations of linagliptin were similar across visits (ranging from ∼7 to 10 nmol/L).
The observed median trough concentrations in the controls were 4.2 (0.0 to 5.7) mg/L.
To determine the incidence of vancomycin-associated nephrotoxicity in children and to examine potential risk factors for nephrotoxicity, including average serum trough concentrations ≥15 mg/L.
70 The average trough plasma rilpivirine concentration was 52 ng/mL two weeks after switching therapy.
70 For weeks 4 12, the average trough plasma rilpivirine concentration was 66 84 ng/mL.
Table 3 reports the mean and 10th percentile trough concentrations for the simulated regimens.
Most patients with trough concentrations below median values achieved SVR.
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