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An average daily and average total dose was calculated for each year as mean ± SE for all experiments reported in the respective year.
The average total dose of CDDP and radiation was 230 mg (median 220 mg, range: 75 375) and 40.5 Gy (median 32.4, range: 30 61.2), respectively.
The resulting graph does not change when the average total dose is used instead of average daily dose (data not shown).
The average total dose of insulin required during the entire presurgery period was 47.5 units/patient compared with 90.7 units/patient in the postsurgery period (P = 0.20 between periods).
The total Dox dose was assumed to be ⩽350 mg m−2, which is 50 mg m−2 above the average total dose for six cycles of ABVD chemotherapy.
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The mean total doses per subject was 2.4 for 6 months, and the mean monthly average dose per subject was 0.5.
The average iAs fraction was then multiplied by the average total As dose from food and summed with the daily As dose from drinking water in order to estimate the amount of iAs ingested.
Both etoricoxib doses (120 mg and 90 mg) were superior to placebo in the co-primary endpoint of average total daily dose of morphine over Days 1 to 3 (p < 0.001); morphine consumption was 31% and 34% less per day, averaged over the first 3 days, in patients treated with etoricoxib 120 mg and 90 mg, respectively, vs. placebo (Table 2).
Atropine was administered during 3.4 ± 2.1 days and the average total atropine dose was 79.1 ± 62.9 mg.
Co-primary endpoints included Average Pain Intensity Difference at Rest over Days 1 3 (0- to 10-point NRS) and Average Total Daily Dose of Morphine over Days 1 3.
In this study we administered 111 MBq Zr-rituximab that resulted in an average total effective dose of 45.5 mSv, which is justifiable within the context of subsequent RIT with administration of 14.8 MBq/kg of Y-rituximab (1,184 MBq for a body weight of 80 kg), resulting in an average total effective dose of 1.03 Sv for RIT.
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