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The average tidal volume was of 443.9 ml (range 431-457) that corresponds to 7.5 ml per kilogram of predicted body weight (IC 95%%: 7,35-7,66).
Average tidal volume showed a linear relation with two year survival, such that even a relatively small decrease in average tidal volume over stay in the intensive care unit was independently associated with an important decrease in risk of mortality.
However, the standard care group included a ventilation strategy with an average tidal volume in excess of 11 ml/kg and no PEEP [ 6].
We also recorded total intraoperative volumes of fluids administered, postoperative fluid balance and average tidal volume and positive end-expiratory pressure.
In the standard care group of this study, the average tidal volume of > 11 ml/kg and PEEP was not used.
Moreover, average tidal volume showed an independent linear relation with two year survival, with an 18% relative increase in the risk of mortality over two years for each 1 mL/kg predicted body weight increase in average tidal volume over the duration of mechanical ventilation.
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The average tidal volumes for technique 1 ranged from 438 to 604 ml.
In a larger and more recent trial, Sachdeva et al. reported that in 125 patients administered rocuronium post-induction, average tidal volumes increased from 525 (116) ml to 586 (129) ml (p < 0.001) [ 13].
The mean tidal volume was 9.8 ml/predicted body weight.
Median tidal volume was 500 ml (IQR 450-550).
Estimate the average expired tidal volume and identify predictive factors of NIV failure.
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